Issue 18, 2024

Facile synthesis of α-sulfonyl ketoximes from alkenes using sodium sulfinate and NaNO2 in water

Abstract

A novel synthesis method for α-sulfonyl ketoximes from alkenes, sodium sulfinate, and NaNO2 in water has been introduced. This intermolecular three-component approach facilitates the one-step formation of C–N and C–S bonds under mild conditions, offering a new, rapid, and straightforward route to α-sulfonyl ketoximes.

Graphical abstract: Facile synthesis of α-sulfonyl ketoximes from alkenes using sodium sulfinate and NaNO2 in water

Supplementary files

Article information

Article type
Research Article
Submitted
18 Jun 2024
Accepted
16 Jul 2024
First published
16 Jul 2024

Org. Chem. Front., 2024,11, 5054-5060

Facile synthesis of α-sulfonyl ketoximes from alkenes using sodium sulfinate and NaNO2 in water

Z. Zhang, N. Zhu and T. Liu, Org. Chem. Front., 2024, 11, 5054 DOI: 10.1039/D4QO01108B

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